Palliative Care

Fundamentals The research project
InAdvance logo

The project Patient-centred pathways of early palliative care, supportive ecosystems and appraisal standard (InAdvance) inadvanceproject.eu proposes a model of palliative care (PC) based on early integration and personalised pathways addressed specifically to older people with complex chronic conditions. Thus, the overall aim of InAdvance is to improve the benefit of PC through the design of effective, replicable and cost-effective early PC interventions centred-on and oriented-by the patients. To achieve this main goal, InAdvance will produce the following evidence-based outputs to assist care professionals, service managers and policy and decision-makers in their scalability and replicability: a) stratification tools to identify potential beneficiaries of early PC actions; b) optimised interventions co-designed by needs and preferences from patients and their relatives; c) eHealth tools addressed to empower palliative patients ecosystem; d) policy recommendations and clinical guidelines addressed to service providers and policy and decision-makers; e) an appraisal standard and dashboard facilitating a critical and comprehensive comparison between actions and interventions derived from the project.

The predictive models

The predictive models in this website are the result of a joint research effort performed by the Biomedical Data Science Lab (BDSLab) in collaboration with Hospital Universitari i Politècnic La Fe, both from Valencia (Spain) in the context of the inAdvance project. All of the predictive models use information obtained for each patient on the hospital admission

The three available predictive models are:

  • One-year mortality: Predicts the probability of a patient dying in one year since its admissions to the hospital.
  • Survival regression: Estimates the amount of days from admission to exitus. Used to complement the informacion provided by the one-year mortality model.
  • Frailty classification: Predicts the probability of a patient being frail in one year.

The three available models have been trained both the same way: in first place we performed a recursive feature elimination process per model, selecting the 20 most important variables according to the GINI importance in a random forest. After that, a gridsearch was conducted to find an optimal hyperparams combination using the Gradient Boosting Machine (GBM) as base model. Finally, we evaluated the performance of the models using a k-fold (k=10) validation. The results of the study will be available soon as a preprint here: COMING SOON!. The models exposed in this website are trained with most of the original samples.